Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B
CUI: C0019202
Disease: Hepatolenticular Degeneration
Hepatolenticular Degeneration 		1.000 GeneticVariation LHGDN [Wilson disease: clinical and biological aspects]. 16230279

2006
Entrez Id: 2147
Gene Symbol: F2
F2
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.500 GeneticVariation LHGDN [Venous thromboembolic events in surgery: a role of genetic disorders]. 18368843

2008
Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.500 GeneticVariation LHGDN [Venous thromboembolic events in surgery: a role of genetic disorders]. 18368843

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.080 AlteredExpression LHGDN [Value of P-glycoprotein and glutathione S-transferase-pi as chemo-resistant indicators in ovarian cancers]. 11783115

2001
Entrez Id: 8647
Gene Symbol: ABCB11
ABCB11
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.010 AlteredExpression LHGDN [Value of P-glycoprotein and glutathione S-transferase-pi as chemo-resistant indicators in ovarian cancers]. 11783115

2001
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.600 AlteredExpression LHGDN [Use of silicon chip technology to detect protein-based tumor markers in bladder cancer]. 17593336

2007
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0010278
Disease: Craniosynostosis
Craniosynostosis 		0.200 GeneticVariation LHGDN [Typical features of craniofacial growth of the FGFR3-associated coronal synostosis syndrome (so-called Muenke craniosynostosis)]. 12764678

2003
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1
CUI: C0023531
Disease: Leukoplakia
Leukoplakia 		0.010 AlteredExpression LHGDN [Type IV collagen and C-erbB-2 expression in oral candidal leukoplakia]. 11776869

1999
Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.100 AlteredExpression LHGDN [Treatment outcome of multidrug resistance related mRNA expression and c-jun-N-terminal kinase activity in patients with acute myeloid leukemia]. 18094581

2007
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
CUI: C0600467
Disease: Neurogenic Inflammation
Neurogenic Inflammation 		0.010 Biomarker LHGDN [Transient receptor potential (TRP) channel and cough]. 18552442

2008
Entrez Id: 2173
Gene Symbol: FABP7
FABP7
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.040 AlteredExpression LHGDN [Transcriptome analyses in renal cell carcinoma. Combination of laser microdissection and microarrays]. 17646957

2007
Entrez Id: 1612
Gene Symbol: DAPK1
DAPK1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.330 Biomarker LHGDN [Transcription TIMP3, DAPk1 and AKR1B10 genes in squamous cell lung cancer]. 17209433

2007
Entrez Id: 7078
Gene Symbol: TIMP3
TIMP3
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.030 Biomarker LHGDN [Transcription TIMP3, DAPk1 and AKR1B10 genes in squamous cell lung cancer]. 17209433

2007
Entrez Id: 57016
Gene Symbol: AKR1B10
AKR1B10
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.020 Biomarker LHGDN [Transcription TIMP3, DAPk1 and AKR1B10 genes in squamous cell lung cancer]. 17209433

2007
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
CUI: C0023418
Disease: leukemia
leukemia 		0.030 AlteredExpression LHGDN [Transcription levels of the MYCN gene in blood cell subpopulations of Patients with leukemia]. 18610847

2008
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0282193
Disease: Iron Overload
Iron Overload 		0.600 Biomarker LHGDN [To prevent and cure the iron overloads, the hopes of hepcidin]. 16962038

2006
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0018995
Disease: Hemochromatosis
Hemochromatosis 		0.400 GeneticVariation LHGDN [To prevent and cure the iron overloads, the hopes of hepcidin]. 16962038

2006
Entrez Id: 11093
Gene Symbol: ADAMTS13
ADAMTS13
CUI: C0034155
Disease: Purpura, Thrombotic Thrombocytopenic
Purpura, Thrombotic Thrombocytopenic 		0.700 Biomarker LHGDN [Thrombosis and ADAMTS13 exclusively produced in the liver]. 18833927

2008
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
CUI: C0030305
Disease: Pancreatitis
Pancreatitis 		0.700 GeneticVariation LHGDN [Three cases of hereditary pancreatitis in two households in the same family associated with R122H mutation in cationic trypsinogen gene]. 17641559

2007
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 GeneticVariation LHGDN [The XbaI and PvuII gene polymorphisms of the estrogen receptor alpha gene in Chinese women with breast cancer]. 15842934

2005
Entrez Id: 2678
Gene Symbol: GGT1
GGT1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.100 AlteredExpression LHGDN [The value of gamma-glutamyl transpeptidase mRNA typing in monitoring carcinogensis of heptocytes]. 11940314

2002
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.360 GeneticVariation LHGDN [The use of discrete characters in discriminant analysis for diagnosis of pulmonary tuberculosis and for classification of patients differing in treatment efficiency based on polymorphisms at nine codominant loci-HP, GC, TF, PI, PGM1, GLO1, C3, ACP1 and ESD]. 12942785

2003
Entrez Id: 2638
Gene Symbol: GC
GC
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.080 GeneticVariation LHGDN [The use of discrete characters in discriminant analysis for diagnosis of pulmonary tuberculosis and for classification of patients differing in treatment efficiency based on polymorphisms at nine codominant loci-HP, GC, TF, PI, PGM1, GLO1, C3, ACP1 and ESD]. 12942785

2003
Entrez Id: 7018
Gene Symbol: TF
TF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.010 GeneticVariation LHGDN [The use of discrete characters in discriminant analysis for diagnosis of pulmonary tuberculosis and for classification of patients differing in treatment efficiency based on polymorphisms at nine codominant loci-HP, GC, TF, PI, PGM1, GLO1, C3, ACP1 and ESD]. 12942785

2003
Entrez Id: 2739
Gene Symbol: GLO1
GLO1
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.010 GeneticVariation LHGDN [The use of discrete characters in discriminant analysis for diagnosis of pulmonary tuberculosis and for classification of patients differing in treatment efficiency based on polymorphisms at nine codominant loci-HP, GC, TF, PI, PGM1, GLO1, C3, ACP1 and ESD]. 12942785

2003